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Zopiclone Long Term Use Side Effect: You Need To Know

Zopiclone is marketed under these brand names: Imovane, Zimovane, and Dopareel. If we think about drugs that have soothing properties, lorazepam, Xanax, or Activan comes to mind. Zopiclone is different from these hypnotic drugs.

Imovane, Zimovane, and Dopareel are all drugs that help in the treatment of anxiety or insomnia related disorders but do not belong to the benzodiazepine group. Like the other hypnotic drugs, overuse, or long term use of Zopiclone will create side effects.
Patients need guidelines about the best way to use Zopiclone.

What it means

If we think about the most common disease that people around us are suffering from is clearly from mental sickness. The majority of the people surrounding us are in some ways under stress, cannot sleep at night, things about kinds of stuff, and cannot sleep at night.
All these mental problems lead to anxiety and depression. To help these people, we prescribe drugs that will calm their minds. Zopiclone is the answer to all these psychological pressure.

Zopiclone means relief from insomnia. Patients who are suffering from anxiety cannot sleep at night. They suddenly have a panic attack, thinks about their life too much. Zopiclone helps consumers to fall asleep and also helps the consumer from waking up in the middle of sleep.
Zopiclone modulates the benzodiazepine receptors. By modulating the benzodiazepine receptors, they increase the transmission of neurotransmitter GABA. This increased transmission of GABA helps the central nervous system to relax and get the patients to fall asleep.


Best way to use Zopiclone

Patients who suffer from anxiety, depression cannot fall asleep at night. Because they overthink about a topic, and this stops the central nervous system from producing Neurotransmitters GABA. So the patients get into an irritable or excited state.
Any substance that reduces irritably or excitability is known as a sedative. Zopiclone is a sedative, sleeping pill. With the administration of this drug into the body, the nerves of the central nervous system are relaxed.

Zopiclone is commonly known as prescription sleeping pills. As it is a prescription drug, there is a specific way of taking this medication. Only taking this medicine exactly as the physician instructed should be followed. Avoiding this instruction will cause the side effects of Zopiclone’s long term use.

There are two dosages of this medicine. The oral pills come in 3.75 mg and 7.5 mg in strength. No amount of Zopiclone is permitted to give to the children or patients under 18 years old. In healthy adults commonly, a 7.5mg pill is advised to take before going to sleep at night. On average, all the brands take around one hour to start working.

In elderly patients, 3.75mg dose is advised to take before going to sleep. A lower dose is for elderly patients because of the low liver and kidney function rate. The pill must be taken as a whole. No chewing or crushing of the tablet is allowed. Despite taking medicine every night, the doctor may ask the patient to take the pill every week for a few days. Whatever the doctor suggests, the patient should follow.

Recreational use of Zopiclone

What if the drug that you are using to get rid of anxiety, gives you depression instead? It would be terrible for all. The abuse of Zopiclone does that. There are two types of drug abuse. They are

  • Recreational misuse
  • Long term use without medical advice

Recreational misuse

Recreational misuse is commonly reported for Imovane, Zimovane, and Dopareel. People misuse these drugs by taking them orally, intravenously, or even they mix different brands of Zopiclone with alcohol and then consume it. Zopiclone has hypnotic effects. For recreational purposes, It gives the user a dreamlike effect. They go to a state where the consumer starts to see unreal things. This state is due to a fact known as euphoria.

Some studies suggest that compared to benzodiazepine, this non-benzodiazepine class medicine give a stronger euphoretic effect. The alcohol itself is a sedative when taken with sleeping pills creates a more dreamlike state.
Due to its high use as a recreation drug, Zopiclone belong to the “Z class” drug.

Zopiclone long term use

Most of the addicts who use Zopiclone have become an addict due to long term use. Imovane, Zimovane, and Dopareel all have high addictive properties. So the patients must follow the instructions written in the prescription.

Specialist and compendium both suggest that for any sleeping pill, a minimum dose for a minimum time is to prescribe. The recommended time in prescription must not exceed ten days at most. Because sleeping pills have a high tendency to get addicted, abused, and cause side effects.

Meanwhile, a high percentage of patients are getting addicted to Zopiclone because they are using it in a high dose. In Franch, Zopiclone is one of the top medicine that is purchased using fake prescriptions. So, all in all, we can state that long term use of Zopiclois not recommended nor safe.

Side effects of zopiclone long term use

Zopiclone long term use creates dependence on the drug. The relationship slowly converts into addiction. Also, Zopiclone therapy is stopped; physicians do not suddenly stop giving you medicine. They gradually reduce the dose. Otherwise, there is a possibility of getting withdrawal symptoms.
The significant side effects of zopiclone long term use listed below:

  • 1. Nervous ​​​​system disorders
    a. Bitter taste in mouth
    b. Sleepiness
    c. Dizziness
    d. Headache
  • 2. Respiratory diseases:
    Difficulty in breathing
  • 3. Withdrawal symptoms:
    a. Insomnia
    b. Sweating
    c. Muscle pain
    d. Confusion
    e. Headache
    f. Nightmares
    g. Hallucination

Final thought

Zopiclone is a non-benzodiazepine class sleeping pill. It helps people who have insomnia to fall asleep. Without sleep, patients start to suffer from anxiety. And anxiety is the doorway for other diseases like heart disease, liver malfunction, and kidney diseases to enter.

The common brands available in the market now are all trendy. Physicians recommend them frequently. But they also have high addictive properties.
So patients who are prescribed to take this medicine should follow the prescription and avoid misuse. Pharmacies will never sell this medication without a prescription. The consumer must carry the doctor’s order if he wants to buy Zopiclone.


I'm Dr. Torrez Walker MD over 20 years in the pharmaceutical industry with experience in research Chemicals. Additional experience also covers Sox Testing, process improvements, and technical assessments. Consider responsible highly organized, with strong personal and communication skills; results and profit-oriented. Track record of success managing highly technical, very challenging and complex projects. SAP, Excel and Access Expert.

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